Low levels of vitamin A can cause night blindness and skin disorders and raise your risk of infections. It is needed for healthy skin, normal vision, and healthy intestines.

It helps the immune system fight infections. As with all products, always follow the directions you and your CF care team developed.

ET, or emailing get the most from your vitamin supplements, always take them with a meal or snack that contains fat and your enzymes. If you have questions about affording vitamin supplements, contact CF Foundation Compass by calling 844-COMPASS, Monday through Friday, 9 a.m. Most single nutrient vitamin supplements are available over the counter, although some require a prescription. The combination of vitamin K and D can significantly increase the total BMD and significantly decrease undercarboxylated osteocalcin, and a more favorable effect is expected when vitamin K2 is used.Sometimes a member of your CF care team will ask you to take a single nutrient vitamin supplement, such as vitamin D. Simultaneously, subgroup analysis showed that K2 or vitamin K (not specified) supplement was less than 500 μg d-1, which when combined with vitamin D can significantly increase the total BMD compared with the control group fed a normal diet or the group with no treatment (0.479, 0.101 to 0.858 and 0.570, 0.196 to 0.945). A significant decrease in undercarboxylated osteocalcin (-0.945, -1.113 to -0.778) can be observed with the combination of vitamin K and D.

Vitamin K combined with vitamin D significantly increased the total bone mineral density (BMD): the pooled effect size was 0.316. Previous studies did not draw a consistent conclusion about the effects of vitamin K combined with vitamin D on human skeletal quality.Ī comprehensive search on Web of Science, PubMed, Embase and the Cochrane Library (from 1950 to February 2020) and bibliographies of relevant articles was undertaken, with the meta-analysis of eight randomized controlled trials (RCTs) including a total of 971 subjects.

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